Contents

I: Introduction
Chapter 1. Overview of the immune system
Chapter 2. Cells, organs, and microenvironments of the immune system
Chapter 3. Recognition and response
II: Innate immunity
Chapter 4. Innate immunity
Chapter 5. The complement system
III: Adaptive immunity: antigen receptors and MHC
Chapter 6. The organization and expression of lymphocyte receptor genes
Chapter 7. The major histocompatibility complex and antigen presentation
IV: Adaptive immunity: development
Chapter 8. T-cell development
Chapter 9. B-cell development
V: Adaptive immunity: effector responses
Chapter 10. T-cell activation, helper subset differentiation, and memory
Chapter 11. B-cell activation, differentiation, and memory generation
Chapter 12. Effector responses: antibody- and cell-mediated immunity
Chapter 13. Barrier immunity: the immunology of mucosa and skin
Chapter 14. The adaptive immune response in space and time
VI: The immune system in health and disease
Chapter 15. Allergy, hypersensitivities, and chronic inflammation
Chapter 16. Tolerance, autoimmunity, and transplantation
Chapter 17. Infectious diseases and vaccines
Chapter 18. Immunodeficiency diseases
Chapter 19. Cancer and the immune system
VII: Experimental methods
Chapter 20. Experimental systems and methods.