Contents

Biochemistry: an evolving science
Protein composition and structure
Exploring proteins and proteomes
DNA, RNA, and the flow of genetic information
Exploring genes and genomes
Exploring evolution and bioinformatics
Hemoglobin: portrait of a protein in action
Enzymes: basic concepts and kinetics
Catalytic strategies
Regulatory strategies
Carbohydrates
Lipids and cell membranes
Membrane channels and pumps
Signal-transduction pathways
Metabolism: basic concepts and design
Glycolysis and gluconeogenesis
The citric acid cycle
Oxidative phosphorylation
The light reactions of photosynthesis
The calvin cycle and the pentose phosphate pathway
Glycogen metabolism
Fatty acid metabolism
Protein turnover and amino acid catabolism
The biosynthesis of amino acids
Nucleotide biosynthesis
The biosynthesis of membrane lipids and steroids
The integration of metabolism
DNA replication, repair, and recombination
RNA synthesis and processing
Protein synthesis
The control of gene expression in prokaryotes
The control of gene expression in eukaryotes
Sensory systems
The immune system
Molecular motors
Drug development.