Huntington disease
- Amsterdam Elsevier 2017
- xvi, 297 p. 27 cm.
- Handbook of clinical neurology Vol.144 .
Contents:
SECTION I Basic science 1.Genetics of Huntington disease / M.A. Nance 2.Mechanisms underlying neurodegeneration in Huntington disease: applications to novel disease-modifying therapies / R.L. Margolis SECTION II Clinical aspects 3.Epidemiology of Huntington disease / B.R. Leavitt 4.Statistical modeling of Huntington disease onset / Y. Wang 5.The diagnosis and natural history of Huntington disease / M. Altshuler 6.Cognitive and behavioral changes in Huntington disease before diagnosis / E. Shaw 7.Preclinical motor manifestations of Huntington disease / K.M. Biglan 8.The highly anxious individual presenting for Huntington disease-predictive genetic testing: the psychiatrist's role in assessment and counseling / M. Groves 9.Preimplantation genetics and other reproductive options in Huntington disease / P.C. Sacks 10.Genetic testing for Huntington disease / K.A. Quaid SECTION III Treatment of Huntington disease Contents note continued: 11.Medical treatment of behavioral manifestations of Huntington disease / E. van Duijn 12.Medical management of motor manifestations of Huntington disease / C. T. Loy 13.The role of rehabilitation therapy in Huntington disease / M. Busse 14.Contemporary health care for Huntington disease / L. Goodman 15.The impact of Huntington disease on young people / M. Ellison 16.Making a measurable difference in advanced Huntington disease care / A.K. Rao SECTION IV Experimental therapeutics 17.New symptomatic therapies for Huntington disease / C.M. Testa 18.Motor outcome measures in Huntington disease clinical trials / R. Schubert 19.Cognitive assessment in Huntington disease clinical drug trials / Y. Glikmann-Johnston SECTION V Biomarkers 20.Structural imaging in premanifest and manifest Huntington disease / E.H. Aylward 21.Functional imaging in Huntington disease / D. Eidelberg.