TY  - GEN
AU  - Golan, David E.
AU  - Armstrong, Ehrin J.
AU  - Armstrong, April W. 
TI  - Principles of pharmacology: : the pathophysiologic basis of drug therapy
SN  -  9781451191004
U1  - QV4 
PY  - 2017///
CY  - New Delhi
PB  - Wolters Kluwer
KW  - Pharmacology
KW  - Pharmacological Phenomena
KW  - Physiology, Pathological
KW  - Drug Therapy
N1  - Machine generated contents note: 

SECTION I Fundamental Principles of Pharmacology
1.Drug
Receptor Interactions / David E. Golan
2.Pharmacodynamics / David E. Golan
3.Pharmacokinetics / David E. Golan
4.Drug Metabolism / F. Peter Guengerich
5.Drug Transporters / Keith A. Hoffmaster
6.Drug Toxicity / David E. Golan
7.Pharmacogenomics / Kelan Tantisira
SECTION II Principles of Neuropharmacology
SECTION IIA Fundamental Principles of Neuropharmacology
8.Principles of Cellular Excitability and Electrochemical Transmission / Gary R. Strichartz
9.Principles of Nervous System Physiology and Pharmacology / Daniel H. Lowenstein
SECTION IIB Principles of Autonomic and Peripheral Nervous System Pharmacology
10.Cholinergic Pharmacology / Gary R. Strichartz
11.Adrenergic Pharmacology / David E. Golan
12.Local Anesthetic Pharmacology / Gary R. Strichartz
SECTION IIC Principles of Central Nervous System Pharmacology
Contents note continued: 13.Pharmacology of GABAergic and Glutamatergic Neurotransmission / Eng H. Lo
14.Pharmacology of Dopaminergic Neurotransmission / Victor W. Sung
15.Pharmacology of Serotonergic and Central Adrenergic Neurotransmission / Roy H. Perlis
16.Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System / Daniel H. Lowenstein
17.General Anesthetic Pharmacology / Keith W. Miller
18.Pharmacology of Analgesia / Clifford J. Woolf
19.Pharmacology of Drugs of Abuse / Sachin Patel
SECTION III Principles of Cardiovascular Pharmacology
20.Pharmacology of Cholesterol and Lipoprotein Metabolism / David E. Cohen
21.Pharmacology of Volume Regulation / Seth L. Alper
22.Pharmacology of Vascular Tone / Joseph Loscalzo
23.Pharmacology of Hemostasis and Thrombosis / David E. Golan
24.Pharmacology of Cardiac Rhythm / David E. Clapham
25.Pharmacology of Cardiac Contractility / Ehrin J. Armstrong
Contents note continued: 26.Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure / Ehrin J. Armstrong
SECTION IV Principles of Endocrine Pharmacology
27.Pharmacology of the Hypothalamus and Pituitary Gland / Ursula B. Kaiser
28.Pharmacology of the Thyroid Gland / William W. Chin
29.Pharmacology of the Adrenal Cortex / Gail K. Adler
30.Pharmacology of Reproduction / Robert L. Barbieri
31.Pharmacology of the Endocrine Pancreas and Glucose Homeostasis / Steven E. Shoelson
32.Pharmacology of Bone Mineral Homeostasis / Ehrin J. Armstrong
SECTION V Principles of Chemotherapy
33.Principles of Antimicrobial and Antineoplastic Pharmacology / David E. Golan
34.Pharmacology of Bacterial Infections: DNA Replication, Transcription, and Translation / Donald M. Coen
35.Pharmacology of Bacterial and Mycobacterial Infections: Cell Wall Synthesis / Sarah P. Hammond
Contents note continued: 36.Pharmacology of Fungal Infections / April W. Armstrong
37.Pharmacology of Parasitic Infections / Edward T. Ryan
38.Pharmacology of Viral Infections / Donald M. Coen
39.Pharmacology of Cancer: Genome Synthesis, Stability, and Maintenance / David A. Frank
40.Pharmacology of Cancer: Signal Transduction / David A. Frank
41.Principles of Combination Chemotherapy / David E. Golan
SECTION VI Principles of Inflammation and Immune Pharmacology
42.Principles of Inflammation and the Immune System / April W. Armstrong
43.Pharmacology of Eicosanoids / Charles N. Serhan
44.Histamine Pharmacology / April W. Armstrong
45.Pharmacology of Hematopoiesis and Immunomodulation / George D. Demetri
46.Pharmacology of Immunosuppression / April W. Armstrong
47.Integrative Inflammation Pharmacology: Peptic Ulcer Disease / Helen M. Shields
48.Integrative Inflammation Pharmacology: Asthma / Stephen Lazarus
Contents note continued: 49.Integrative Inflammation Pharmacology: Gout / Lloyd B. Klickstein
SECTION VII Environmental Toxicology
50.Environmental Toxicology / Joshua M. Galanter
SECTION VIII Fundamentals of Drug Development and Regulation
51.Drug Discovery and Preclinical Development / Maarten Postema
52.Clinical Drug Evaluation and Regulatory Approval / Alexander E. Kuta
53.Systematic Detection of Adverse Drug Events / Jerry Avorn
SECTION IX Frontiers in Pharmacology
54.Protein Therapeutics / David E. Golan
55.Drug Delivery Modalities / Robert Langer
N2  - 
Summary:

Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, _offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets. Chapters are integrated into sections that focus on organ systems and therapeutic areas of highest importance. Clear, concise illustrations highlight key points, and drug summary tables offer quick access to essential information"--Publisher's description
ER  -