@book{130120, author = {Turgut, Mehmet and Akhaddar, Ali, }, title = {Tuberculosis of the central nervous system: }, publisher = {Springer,}, year = {2017}, address = {Cham, Switzerland : }, note = {Contents; Part I: General Considerations; 1: Historical Preview and Epidemiology of Tuberculosis; 1.1 Introduction; 1.2 History; 1.3 Epidemiology; 1.4 TB Vaccine; 1.5 Surgical Therapy; 1.6 Antimicrobial Therapy of TB; 1.7 History of Therapy of CNS Tuberculosis; 1.8 History of TB Preventive Therapy; References; 2: Human Genetics of Tuberculosis of the Nervous System; 2.1 Introduction; 2.2 Patients; 2.2.1 Family 1; 2.2.2 Family 2; 2.3 Genetic and Functional Analyses; 2.4 Discussion; References; 3: Pathogenesis of Tuberculosis of the Nervous System; 3.1 Introduction. 3.2 Immune Response in Tuberculosis3.3 Mycobacterium Tuberculosis in the Brain; 3.4 Tuberculous Meningitis (TBM); 3.5 Intracranial Tuberculoma; 3.6 Intracranial Tuberculous Abscess; 3.7 Tuberculous Encephalopathy; 3.8 Tuberculous Spondylitis (Pott's Disease); 3.9 Tuberculous Arachnoiditis; 3.10 Non-osseous Spinal Cord Tuberculosis; References; 4: Pathology of Tuberculosis of the Nervous System (Tuberculous Meningitis, Tuberculoma, Tuberculous Abscess); 4.1 Introduction; 4.2 Pathogenesis of CNS Tuberculosis: Infection to Organ Dissemination. 4.3 Nervous System Involvement in Tuberculosis4.3.1 Tuberculous Meningitis; 4.3.1.1 Introduction; 4.3.1.2 Gross Pathology; 4.3.1.3 Microscopic Pathology; 4.3.2 CNS Tuberculoma; 4.3.2.1 Introduction; 4.3.2.2 Gross Pathology; 4.3.2.3 Microscopic Pathology; 4.3.3 Tuberculous Abscess; 4.3.3.1 Introduction; 4.3.3.2 Gross Pathology; 4.3.3.3 Microscopic Pathology; 4.3.4 Complications of Tuberculous Meningitis; 4.3.5 HIV and CNS Tuberculosis; 4.3.6 Nontubercular Mycobacterial CNS Infection; 4.4 Histopathologic Differential Diagnoses of CNS Tuberculosis. 4.4.1 Acute Inflammatory Pathology4.4.2 Chronic Inflammatory Pathology; 4.5 Diagnostic Tests; 4.5.1 Cerebrospinal Fluid Aspiration; 4.5.2 Biopsy; 4.5.3 Fine Needle Aspirates; References; Part II: Tuberculosis of the Brain and Its Coverings; 5: Scalp and the Calvarium; 5.1 Introduction; 5.2 Scalp Tuberculosis; 5.3 Calvarial Tuberculosis; 5.3.1 Introduction; 5.3.2 Epidemiology; 5.3.3 Pathogenesis; 5.3.4 Role of Trauma and Immune Suppression; 5.3.5 Presentation; 5.3.6 Investigations; 5.3.7 Treatment; References; 6: Dura Mater and Epidural Space; 6.1 Introduction. 6.2 Pathogenesis6.3 Diagnosis; 6.4 Imaging; 6.5 Management; 6.6 Follow-Up; References; 7: Subdural Space of the Brain and Its Coverings; 7.1 Introduction; 7.2 Brief Anatomy of the Intradural Space of the Brain and Its Coverings; 7.3 Tuberculosis of the Subdural Space of the Brain and Its Coverings; 7.3.1 Tuberculous Meningitis; 7.3.2 Etiology; 7.3.3 Diagnosis; 7.3.4 Lumbar Puncture; 7.3.5 Radiological Findings; 7.3.6 Amplification of Nucleic Acid Tests; 7.3.7 CSF Findings; 7.3.8 Treatment; 7.3.9 Prognosis; 7.4 Tuberculous Arachnoiditis; 7.4.1 Signs and Symptoms.} }