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Tuberculosis of the central nervous system: pathogenesis, imaging, and management

By: Turgut, MehmetContributor(s): Akhaddar, Ali [editor] | Garg, Ravin K [editor] | Turgut, Ahmet Tuncay [editor]Publication details: Cham, Switzerland : Springer, 2017Description: x, 633 p. : 26 cmISBN: 9783319507118Subject(s): Tuberculosis | Central nervous system - Diseases | Central nervous system - TuberculosisDDC classification: WL301 Summary: Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.
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Contents;

Part I: General Considerations; 1: Historical Preview and Epidemiology of Tuberculosis; 1.1 Introduction; 1.2 History; 1.3 Epidemiology; 1.4 TB Vaccine; 1.5 Surgical Therapy; 1.6 Antimicrobial Therapy of TB; 1.7 History of Therapy of CNS Tuberculosis; 1.8 History of TB Preventive Therapy; References; 2: Human Genetics of Tuberculosis of the Nervous System; 2.1 Introduction; 2.2 Patients; 2.2.1 Family 1; 2.2.2 Family 2; 2.3 Genetic and Functional Analyses; 2.4 Discussion; References; 3: Pathogenesis of Tuberculosis of the Nervous System; 3.1 Introduction.
3.2 Immune Response in Tuberculosis3.3 Mycobacterium Tuberculosis in the Brain; 3.4 Tuberculous Meningitis (TBM); 3.5 Intracranial Tuberculoma; 3.6 Intracranial Tuberculous Abscess; 3.7 Tuberculous Encephalopathy; 3.8 Tuberculous Spondylitis (Pott's Disease); 3.9 Tuberculous Arachnoiditis; 3.10 Non-osseous Spinal Cord Tuberculosis; References; 4: Pathology of Tuberculosis of the Nervous System (Tuberculous Meningitis, Tuberculoma, Tuberculous Abscess); 4.1 Introduction; 4.2 Pathogenesis of CNS Tuberculosis: Infection to Organ Dissemination.
4.3 Nervous System Involvement in Tuberculosis4.3.1 Tuberculous Meningitis; 4.3.1.1 Introduction; 4.3.1.2 Gross Pathology; 4.3.1.3 Microscopic Pathology; 4.3.2 CNS Tuberculoma; 4.3.2.1 Introduction; 4.3.2.2 Gross Pathology; 4.3.2.3 Microscopic Pathology; 4.3.3 Tuberculous Abscess; 4.3.3.1 Introduction; 4.3.3.2 Gross Pathology; 4.3.3.3 Microscopic Pathology; 4.3.4 Complications of Tuberculous Meningitis; 4.3.5 HIV and CNS Tuberculosis; 4.3.6 Nontubercular Mycobacterial CNS Infection; 4.4 Histopathologic Differential Diagnoses of CNS Tuberculosis.
4.4.1 Acute Inflammatory Pathology4.4.2 Chronic Inflammatory Pathology; 4.5 Diagnostic Tests; 4.5.1 Cerebrospinal Fluid Aspiration; 4.5.2 Biopsy; 4.5.3 Fine Needle Aspirates; References; Part II: Tuberculosis of the Brain and Its Coverings; 5: Scalp and the Calvarium; 5.1 Introduction; 5.2 Scalp Tuberculosis; 5.3 Calvarial Tuberculosis; 5.3.1 Introduction; 5.3.2 Epidemiology; 5.3.3 Pathogenesis; 5.3.4 Role of Trauma and Immune Suppression; 5.3.5 Presentation; 5.3.6 Investigations; 5.3.7 Treatment; References; 6: Dura Mater and Epidural Space; 6.1 Introduction.
6.2 Pathogenesis6.3 Diagnosis; 6.4 Imaging; 6.5 Management; 6.6 Follow-Up; References; 7: Subdural Space of the Brain and Its Coverings; 7.1 Introduction; 7.2 Brief Anatomy of the Intradural Space of the Brain and Its Coverings; 7.3 Tuberculosis of the Subdural Space of the Brain and Its Coverings; 7.3.1 Tuberculous Meningitis; 7.3.2 Etiology; 7.3.3 Diagnosis; 7.3.4 Lumbar Puncture; 7.3.5 Radiological Findings; 7.3.6 Amplification of Nucleic Acid Tests; 7.3.7 CSF Findings; 7.3.8 Treatment; 7.3.9 Prognosis; 7.4 Tuberculous Arachnoiditis; 7.4.1 Signs and Symptoms.

Written and edited by leading international authorities in the field, this book provides an in-depth review of knowledge of tuberculosis of the central nervous system, with emphasis on clinical, diagnostics, and therapeutic features. Tuberculosis, one of the most lethal diseases in human history, still poses a serious threat in the world together with economic and social problems, although a great progress in the fight against this infectious disease in the last century. It covers the full range of tuberculosis of central nervous system and the chapters are organized into six sections: (1) the cranial; (2) the spinal; and (3) the peripheral portions of the nervous system; followed by (4) a section on the laboratory studies in tuberculosis; (5) a section on medical and surgical therapy; and (6) further insights into tuberculosis. This comprehensive reference book will be an ideal source for neurosurgeons, neurologists and specialists upon infectious diseases seeking both basic and more sophisticated information and surgical procedures relating to the complications associated with tuberculosis involving the spine, brain and peripheral nerves.

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