000 06112 a2200253 4500
999 _c129813
_d129813
005 20200903105219.0
008 200903b ||||| |||| 00| 0 eng d
020 _a 9781451191004
082 _aQV4
_bGOL
100 _aGolan, David E.
_91892
245 _aPrinciples of pharmacology:
_bthe pathophysiologic basis of drug therapy
250 _a4th ed.
260 _bWolters Kluwer,
_c2017
_aNew Delhi :
300 _axix, 1020 p. : colour illustrations ;
_c28 cm.
500 _aMachine generated contents note: SECTION I Fundamental Principles of Pharmacology 1.Drug Receptor Interactions / David E. Golan 2.Pharmacodynamics / David E. Golan 3.Pharmacokinetics / David E. Golan 4.Drug Metabolism / F. Peter Guengerich 5.Drug Transporters / Keith A. Hoffmaster 6.Drug Toxicity / David E. Golan 7.Pharmacogenomics / Kelan Tantisira SECTION II Principles of Neuropharmacology SECTION IIA Fundamental Principles of Neuropharmacology 8.Principles of Cellular Excitability and Electrochemical Transmission / Gary R. Strichartz 9.Principles of Nervous System Physiology and Pharmacology / Daniel H. Lowenstein SECTION IIB Principles of Autonomic and Peripheral Nervous System Pharmacology 10.Cholinergic Pharmacology / Gary R. Strichartz 11.Adrenergic Pharmacology / David E. Golan 12.Local Anesthetic Pharmacology / Gary R. Strichartz SECTION IIC Principles of Central Nervous System Pharmacology Contents note continued: 13.Pharmacology of GABAergic and Glutamatergic Neurotransmission / Eng H. Lo 14.Pharmacology of Dopaminergic Neurotransmission / Victor W. Sung 15.Pharmacology of Serotonergic and Central Adrenergic Neurotransmission / Roy H. Perlis 16.Pharmacology of Abnormal Electrical Neurotransmission in the Central Nervous System / Daniel H. Lowenstein 17.General Anesthetic Pharmacology / Keith W. Miller 18.Pharmacology of Analgesia / Clifford J. Woolf 19.Pharmacology of Drugs of Abuse / Sachin Patel SECTION III Principles of Cardiovascular Pharmacology 20.Pharmacology of Cholesterol and Lipoprotein Metabolism / David E. Cohen 21.Pharmacology of Volume Regulation / Seth L. Alper 22.Pharmacology of Vascular Tone / Joseph Loscalzo 23.Pharmacology of Hemostasis and Thrombosis / David E. Golan 24.Pharmacology of Cardiac Rhythm / David E. Clapham 25.Pharmacology of Cardiac Contractility / Ehrin J. Armstrong Contents note continued: 26.Integrative Cardiovascular Pharmacology: Hypertension, Ischemic Heart Disease, and Heart Failure / Ehrin J. Armstrong SECTION IV Principles of Endocrine Pharmacology 27.Pharmacology of the Hypothalamus and Pituitary Gland / Ursula B. Kaiser 28.Pharmacology of the Thyroid Gland / William W. Chin 29.Pharmacology of the Adrenal Cortex / Gail K. Adler 30.Pharmacology of Reproduction / Robert L. Barbieri 31.Pharmacology of the Endocrine Pancreas and Glucose Homeostasis / Steven E. Shoelson 32.Pharmacology of Bone Mineral Homeostasis / Ehrin J. Armstrong SECTION V Principles of Chemotherapy 33.Principles of Antimicrobial and Antineoplastic Pharmacology / David E. Golan 34.Pharmacology of Bacterial Infections: DNA Replication, Transcription, and Translation / Donald M. Coen 35.Pharmacology of Bacterial and Mycobacterial Infections: Cell Wall Synthesis / Sarah P. Hammond Contents note continued: 36.Pharmacology of Fungal Infections / April W. Armstrong 37.Pharmacology of Parasitic Infections / Edward T. Ryan 38.Pharmacology of Viral Infections / Donald M. Coen 39.Pharmacology of Cancer: Genome Synthesis, Stability, and Maintenance / David A. Frank 40.Pharmacology of Cancer: Signal Transduction / David A. Frank 41.Principles of Combination Chemotherapy / David E. Golan SECTION VI Principles of Inflammation and Immune Pharmacology 42.Principles of Inflammation and the Immune System / April W. Armstrong 43.Pharmacology of Eicosanoids / Charles N. Serhan 44.Histamine Pharmacology / April W. Armstrong 45.Pharmacology of Hematopoiesis and Immunomodulation / George D. Demetri 46.Pharmacology of Immunosuppression / April W. Armstrong 47.Integrative Inflammation Pharmacology: Peptic Ulcer Disease / Helen M. Shields 48.Integrative Inflammation Pharmacology: Asthma / Stephen Lazarus Contents note continued: 49.Integrative Inflammation Pharmacology: Gout / Lloyd B. Klickstein SECTION VII Environmental Toxicology 50.Environmental Toxicology / Joshua M. Galanter SECTION VIII Fundamentals of Drug Development and Regulation 51.Drug Discovery and Preclinical Development / Maarten Postema 52.Clinical Drug Evaluation and Regulatory Approval / Alexander E. Kuta 53.Systematic Detection of Adverse Drug Events / Jerry Avorn SECTION IX Frontiers in Pharmacology 54.Protein Therapeutics / David E. Golan 55.Drug Delivery Modalities / Robert Langer.
520 _a Summary: Highly regarded by both students and instructors, Principles of Pharmacology: The Pathophysiologic Basis of Drug Therapy, 4th Edition, _offers an integrated mechanism-based and systems-based approach to contemporary pharmacology and drug development. An easy-to-follow format helps first- and second-year students grasp challenging concepts quickly and efficiently. Each chapter presents a clinical vignette illustrating a therapeutic problem within a physiologic or biochemical system; followed by a discussion of the biochemistry, physiology, and pathophysiology of the system; and concluding with a presentation of the pharmacology of the drugs and drug classes that activate or inhibit the system by interacting with specific molecular and cellular targets. Chapters are integrated into sections that focus on organ systems and therapeutic areas of highest importance. Clear, concise illustrations highlight key points, and drug summary tables offer quick access to essential information"--Publisher's description.
650 _aPharmacology
_91977
650 _aPharmacological Phenomena
_91978
650 _aPhysiology, Pathological
_91979
650 _aDrug Therapy
_91980
700 _aArmstrong, Ehrin J.
_eeditor
_91981
700 _aArmstrong, April W.
_eeditor
_91982
942 _cBK