000			04211 a2200277 4500
999			_c130108 _d130108
003			OSt
005			20210308124401.0
008			210302b ||||| |||| 00| 0 eng d
020			_a9783030060879
082			_aWL301 _bTUR
100			_aTurgut, Mehmet _93222
245			_aFungal infections of the central nervous system: _bpathogens, diagnosis, and management
260			_aCham, Switzerland : _bSpringer, _c2019
300			_axii, 479 p. :
500			_aContents: INTRODUCTION SECTION I: GENERAL CONSIDERATIONS Historical aspects of fungal infections Epidemiology of fungal infections Morphological classification of fungal infections (yeasts, molds, dimorphic) Pathogenesis of fungal infections Predisposing factors Histopathology Molecular genetics and genomics of fungal infections SECTION II: FUNGAL PATHOGENS: PATHOGENESIS, PATHOLOGY AND DIAGNOSIS Chapter 8: Aspergillosis Candidiasis Mucormycosis Histoplasmosis and coccidioidomycosis Cryptococcosis Blastomycosis and phaeohyphomycosis Onychomycosis epeat: initial; background-attachment: initial; background-origin: initial; background-clip: initial;">Emmonsiosis Cladophialophora bantiana Cladosporidium, Fusarium spp, Bipolaris hawaiiensis, Schizophyllum commune, Mycoplasma hominis, Scedosporium apiospermum SECTION III: CLINICAL SYNDROMES OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS Meningitis and meningo-encephalitis Raised intracranial pressure Hydrocephalus Intracranial space occupying lesions Skull-base syndromes Orbito-rhino-cerebral syndrome Cavernous sinus syndrome Intracranial fungal aneurysms Acute ischemic or hemorrhagic stroke syndromes Spinal syndromes SECTION III: RADIOLOGICAL FINDINGS OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS Magnetic resonance imaging Positron emission tomography-computed tomography Imaging findings of fungal infections of the cranial and peripheral nerves Imaging findings of fungal infections of sinuses extending into brain Imaging findings of fungal infections of spine and spinal cord SECTION IV: THERAPY OF FUNGAL INFECTIONS INVOLVING CENTRAL NERVOUS SYSTEM AND ITS COVERINGS Antifungals: from genomics to resistance and the development of novel agents Surgical therapy Prognosis of fungal infections involving the central nervous system and its coverings SECTION VI: FURTHER INSIGHTS INTO FUNGAL INFECTIONS In vitro and animal models of fungal infections oReal-time PCR: advanced technologies and applications Next-generation sequencing: current technologies and applications Current innovations and future trends CONCLUSIONS.
520			_aThis book provides comprehensive information on fungal infections of the central nervous system (CNS). Fungal infections are still a major public health challenge for most of the developing world and even for developed countries due to the rising numbers of immune compromised patients, refugee movements, and international travel. Although fungal infections involving the CNS are not particularly common, when they do occur, the results can be devastating in spite of recent advances and currently available therapies. Further, over the past several years, the incidence of these infections has seen a steep rise among immunodeficient patients. In this context, aggressive surgery remains the mainstay of management, but conservative antifungal drug treatment complemented by aggressive surgical debridement may be necessary. Yet the optimal management approach to fungal infections of the CNS remains controversial, owing to the limited individual experience and the variable clinical course of the conditions. Addressing that problem, this comprehensive book offers the ideal resource for neurosurgeons, neurologists and other specialists working with infectious diseases.
650			_aMycoses _93258
650			_aCentral nervous system - Infections _93259
650			_aNervous system - Surgery _93260
650			_aOtolaryngology _93261
650			_aMedical radiology _93262
650			_aEmerging infectious diseases _93263
700			_aChalla, Sundaram _eeditor _93264
700			_aAkhaddar, Ali _eeditor _93265
942			_cBK