000 | 02299 a2200277 4500 | ||
---|---|---|---|
005 | 20240612114210.0 | ||
008 | 240612b ||||| |||| 00| 0 eng d | ||
020 | _a9781118874943 | ||
082 |
_aW20.55.C5 _bMAC |
||
100 |
_aMachin, David _936323 |
||
245 | _aSample size tables for clinical, laboratory and epidemiology studies | ||
250 | _a4th ed. | ||
260 |
_bWiley, _c2018 _aHoboken, New Jersey : |
||
300 |
_aviii, 390 p. : _c24 cm. |
||
500 | _aContent: 1 Basic Design Considerations 1 2 Further Design Considerations 29 3 Binary Outcomes 41 4 Ordered Categorical Outcomes 55 5 Continuous Outcomes 67 6 Rate Outcomes 81 7 Survival Time Outcomes 97 8 Paired Binary, Ordered Categorical and Continuous Outcomes 115 9 Confidence Intervals 135 10 Repeated Outcome Measures 155 11 Non?]Inferiority and Equivalence 167 12 Cluster Designs 193 13 Stepped Wedge Designs 211 14 More than Two Groups Designs 225 15 Genomic Targets and Dose?]Finding 235 16 Feasibility and Pilot Studies 247 17 Therapeutic Exploratory Trials: Single Arm with Binary Outcomes 265 18 Therapeutic Exploratory Trials: Survival, Dual Endpoints, Randomised and Genomic Targets 281 19 The Correlation Coefficient 303 20 Observer Agreement Studies 315 21 Reference Intervals and Receiver Operating Curves 337 22 Sample Size Software 359 Cumulative References 361 Index | ||
520 | _a Summary: This book provides statisticians and researchers with the statistical tools - equations, formulae and numerical tables - to design and plan clinical studies and carry out accurate, reliable and reproducible analysis of the data so obtained. There is no way around this as incorrect procedure in clinical studies means that the researcher's paper will not be accepted by a peer-reviewed journal. Planning and analysing clinical studies is a very complicated business and this book provides indispensible factual information. | ||
650 |
_aClinical trials _936357 |
||
650 |
_aResearch design _936358 |
||
650 |
_aSample size _936359 |
||
650 |
_aStatistical methods _936360 |
||
700 |
_aCampbell, Michael J. _936361 |
||
700 |
_aTan, Say Beng _936362 |
||
700 |
_aTan, Sze Huey _936363 |
||
710 |
_aProQuest _936364 |
||
942 | _cBK | ||
999 |
_c187344 _d187344 |